HIV

NATURE 455 (2008)

EMD-5021:

Molecular Structure of the Native HIV-1 gp120 trimer bound to b12: Membrane region (Liu J, Bartesaghi A, Borgnia MJ, Sapiro G, Subramaniam S)

NAT.COMMUN. 6 (2015)

EMD-3067:

cryoEM reconstruction of 3BC315 Fab in complex with BG505 SOSIP.664 Env trimer (Lee JH, Leaman DP, Kim AS, Torrents de la Pena A, Sliepen K, Yasmeen A, Derking R, Ramos A, de Taeye SW, Ozorowski G, Klein F, Burton DR, Nussenzweig MC, Poignard P, Moore JP, Klasse PJ, Sanders RW, Zwick MB, Wilson IA, Ward AB)

PROC.NAT.ACAD.SCI.USA (2015)

EMD-3059:

ZM197 SOSIP.664 trimer in complex with VRC01 Fab (Julien JP, Lee JH, Ozorowski G, Hua Y, Torrents de la Pena A, de Taeye SW, Nieusma T, Cupo A, Yasmeen A, Golabek M, Pugach P, Klasse PJ, Moore JP, Sanders RW, Ward AB, Wilson IA)

STRUCTURE 23 (2015)

EMD-3120:

cryoEM reconstruction of bnAb PGT128 in complex with BG505 SOSIP.664 Env trimer (Lee JH, de Val N, Lyumkis D, Ward AB)

STRUCTURE (2015)

EMD-3121:

cryoEM reconstruction of bnAb PGT128 in complex with BG505 SOSIP.664 Env trimer at 4.4 Angstrom resolution (Lee JH, de Val N, Lyumkis D, Ward AB)

CELL 162 (2015)

EMD-3086:

negative stain EM of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195 (Scharf L, Wang H, Gao H, Chen S, McDowall A, Bjorkman P)

CELL 162 (2015)

EMD-3096:

cryo-ET subtomogram averaging of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195 (Scharf L, Wang H, Gao H, Chen S, McDowall A, Bjorkman P)

To Be Published

EMD-2657:

TEM of uncleaved soluble HIV envelope proteins (Arnold P, Himmels P, Weiss S, Decker TM, Markl J, Gatterdam V, Tampe R, Bartholomeaus P, Dietrich U, Duerr R)

CELL 159 (2015)

EMD-2753:

PGT124 in complex with BG505 SOSIP.664 Env trimer (Garces F, Sok D, Kong L, McBride R, Kim HJ, Saye-Francisco KF, Julien J-P, Hua Y, Cupo A, Moore JP, Ward AB, Paulson JC, Burton DR, Wilson IA)

CELL REP. 11 (2015)

EMD-6293:

JRFL gp140 NFL2P unliganded (Sharma SK, de Val N, Bale S, Guenaga J, Tran K, Feng Y, Dubrovskaya V, Ward AB, Wyatt RT)

CELL REP. 11 (2015)

EMD-6294:

Bg505 gp140 NFL2P unliganded (Sharma SK, de Val N, Bale S, Guenaga J, Tran K, Feng Y, Dubrovskaya V, Ward AB, Wyatt RT)

CELL REP. 11 (2015)

EMD-6295:

JRFL gp140 NFL2P liganded to PGV04 (Sharma SK, de Val N, Bale S, Guenaga J, Tran K, Feng Y, Dubrovskaya V, Ward AB, Wyatt RT)

PLOS PATHOG. 11 (2015)

EMD-2853:

3BNC117 Fab in complex with BG505 SOSIP.664 Trimer (Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien J-P, Lee JH, van Montfort T, de Taeye SW, Connors M, Burton DR, Wilson IA, Klasse PJ, Ward AB, Moore JP, Sanders RW)

PLOS Pathogens 11 (2015)

EMD-6190:

Negative stain electron microscopy of unliganded JRFL SOSIP (Guenaga J, de Val N, Tran K, Feng Y, Satchwell K, Ward AB, Wyatt RT)

eLife 4 (2014)

EMD-6231:

The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA (Booth DS, Cheng Y, Frankel AD)

PROC.NAT.ACAD.SCI.USA (2013)

EMD-5552:

Molecular structure of the native HIV-1 Env trimer bound to m36: Spike region (Meyerson JR, Tran EE, Kuybeda O, Chen W, Dimitrov DS, Gorlani A, Verrips T, Lifson JD, Subramaniam S)

NATURE 517 (2015)

EMD-2706:

The structure of the immature HIV-1 capsid in intact virus particles at sub-nm resolution (Schur FKM, Hagen WJH, Rumlova M, Ruml T, Mueller B, Kraeusslich H-G, Briggs JAG)

NATURE 517 (2015)

EMD-2707:

The structure of the immature M-PMV capsid in intact virus particles (Schur FKM, Hagen WJH, Rumlova M, Ruml T, Mueller B, Kraeusslich H-G, Briggs JAG)

NATURE 515 (2014)

EMD-2672:

35O22 Fab in complex with BG505 SOSIP.664 Trimer (Huang J, Kang BH, Pancera M, Lee JH, Tong T, Feng Y, Georgiev IS, Chuang GY, Druz A, Doria-Rose NA, Laub L, Sliepen K, van Gils MJ, de la Pena AT, Derking R, Klasse PJ, Migueles SA, Bailer RT, Alam M, Pugach P, Haynes BF, Wyatt RT, Sanders RW, Binley JM, Ward AB, Mascola JR, Kwong PD, Connors M)

Retrovirology 11 (2014)

EMD-2659:

TEM of uncleaved soluble HIV envelope proteins (Arnold P, Himmels P, Weiss S, Decker TM, Markl J, Gatterdam V, Tampe R, Bartholomeaus P, Dietrich U, Durr R)

PLOS PATHOG. 9 (2013)

EMD-5982:

Structure of 2G12 (Fab)2 in Complex with Soluble and Fully Glycosylated HIV-1 Env by Negative-Stain Single Particle Electron Microscopy (Murin CD, Julien JP, Sok D, Stanfield RL, Khayat R, Cupo A, Moore JP, Burton DR, Wilson IA, Ward AB)

J.VIROL. 88 (2014)

EMD-5983:

PROC.NAT.ACAD.SCI.USA (2014)

EMD-2638:

Cryo-electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly. (Bharat TA, Castillo-Menendez LR, Hagen WJ, Lux V, Igonet S, Schorb M, Schur FK, Krauesslich HG, Briggs JA)

Cell Rep. 7 (2014)

EMD-2625:

Negative stain reconstruction of 8ANC195 Fab in complex with BG505 SOSIP.664 trimer (Scharf L, Scheid JF, Lee JH, West AP, Chen C, Gao H, Gnanapragasam PN, Mares R, Seaman MS, Ward AB, Nussenzweig MC, Bjorkman PJ)

IMMUNITY 40 (2014)

EMD-5918:

Negative stain reconstruction of PGT151 Fab in complex with BG505 Env with transmembrane region (Blattner C, Lee JH, Sliepen K, Derking R, Falkowska E, de la Pena AT, Cupo A, Julien JP, van Gils M, Lee PS, Peng W, Paulson JC, Poignard P, Burton DR, Moore JP, Sanders RW, Wilson IA, Ward AB)

NATURE 509 (2014)

EMD-5856:

Negative stain reconstruction of HIV envelope glycoprotein BG505 SOSIP.664 in complex with CAP256-VRC26.09 Fab (Doria-Rose NA, Schramm CA, Gorman J, Moore PL, Bhiman JN, Dekosky BJ, Ernandes MJ, Georgiev IS, Kim HJ, Pancera M, Staupe RP, Altae-Tran HR, Bailer RT, Crooks ET, Cupo A, Druz A, Garrett NJ, Hoi KH, Kong R, Louder MK, Longo NS, McKee K, Nonyane M, O’Dell S, Roark RS, Rudicell RS, Schmidt SD, Sheward DJ, Soto C, Wibmer CK, Yang Y, Zhang Z, Comparative Sequencing NISC, Mullikin JC, Binley JM, Sanders RW, Wilson IA, Moore JP, Ward AB, Georgiou G, Williamson C, Abdool Karim SS, Morris L, Kwong PD, Shapiro L, Mascola JR)

SCIENCE 342 (2013)

EMD-5779:

Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs (Lyumkis D, Julien JP, de Val N, Cupo A, Potter CS, Klasse PJ, Burton DR, Sanders RW, Moore JP, Carragher B, Wilson IA, Ward AB)

NAT.STRUCT.MOL.BIOL. (2013)

EMD-2484:

Pre-fusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy (Bartesaghi A, Merk A, Borgnia MJ, Milne JLS, Subramaniam S)

PLOS PATHOG. 9 (2013)

EMD-2427:

Negative stain Electron Microscopy of BG505 SOSIP.664 gp140 in complex with PGV04 (Sanders RW, Derking R, Cupo A, Julien JP, Yasmeen A, de Val N, Kim HJ, Blattner C, Torrents A, Korzun J, Golabek M, de los Reyes K, Ketas TJ, van Gils MJ, King CR, Wilson IA, Ward AB, Klasse PJ, Moore JP)

PLOS PATHOG. 9 (2013)

EMD-5723:

Negative stain Electron Microscopy of Bg505 SOSIP.664 in complex with sCD4 and 17b (Sanders RW, Derking R, Cupo A, Julien JP, Yasmeen A, de Val N, Kim HJ, Blattner C, de la Pena AT, Korzun J, Golabek M, de Los Reyes K, Ketas TJ, van Gils MJ, King CR, Wilson IA, Ward AB, Klasse PJ, Moore JP)

J.VIROL. 87 (2013)

EMD-5680:

Cryo-electron microscopy of a trimeric soluble HIV Env construct, gp140 SOSIP, in complex with Fab Z13e1 (Harris AK, Bartesaghi A, Milne JL, Subramaniam S)

J.VIROL. 87 (2013)

EMD-5700:

Negative stained image reconstruction of HIV KNH11444 subtype A SOSIP.681 (Klasse PJ, Depetris RS, Pejchal R, Julien JP, Khayat R, Lee JH, Marozsan AJ, Cupo A, Cocco N, Korzun J, Yasmeen A, Ward AB, Wilson IA, Sanders RW, Moore JP)

J.VIROL. 87 (2013)

EMD-5701:

Negative stained image reconstruction of HIV KNH11444 subtype A SOSIP.681.dV1V2V3 (Klasse PJ, Depetris RS, Pejchal R, Julien JP, Khayat R, Lee JH, Marozsan AJ, Cupo A, Cocco N, Korzun J, Yasmeen A, Ward AB, Wilson IA, Sanders RW, Moore JP)

J.VIROL. 87 (2013)

EMD-5702:

Negative stained image reconstruction of HIV KNH11444 subtype A SOSIP.681 in complex with Fab fragment of VRC PG04 monoclonal antibody (Klasse PJ, Depetris RS, Pejchal R, Julien JP, Khayat R, Lee JH, Marozsan AJ, Cupo A, Cocco N, Korzun J, Yasmeen A, Ward AB, Wilson IA, Sanders RW, Moore JP)

J.VIROL. 87 (2013)

EMD-5703:

Negative stained image reconstruction of HIV KNH11444 subtype A SOSIP.681.dV1V2V3 in complex with Fab fragment of VRC PG04 monoclonal antibody (Klasse PJ, Depetris RS, Pejchal R, Julien JP, Khayat R, Lee JH, Marozsan AJ, Cupo A, Cocco N, Korzun J, Yasmeen A, Ward AB, Wilson IA, Sanders RW, Moore JP)

PLOS PATHOG. 9 (2013)

EMD-5624:

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans (Julien JP, Sok D, Khayat R, Lee JH, Doores KJ, Walker LM, Ramos A, Diwanji DC, Pejchal R, Cupo A, Katpally U, Depetris RS, Stanfield RL, McBride R, Marozsan AJ, Paulson JC, Sanders RW, Moore JP, Burton DR, Poignard P, Ward AB, Wilson IA)

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